NFL Odds, Picks, Predictions For Colts vs. Jaguars: Indianapolis Made Huge Favorite in Must-Win Week 18 Matchupby ActionNetworkJanuary 8, 2022January 8, 2022In search of Colts vs. Jaguars odds? We’ve outlined the spread and over/under in our guide to betting this NFL matchup. Leave a Reply Cancel replyYou must be logged in to post a comment.