Louisville vs. Wake Forest Odds Louisville Odds +6.5 (-105) Wake Forest Odds -6.5 (-115) Moneyline +205 / -255 Over/Under 61.5 (-115 / -105) Time 12:30 p.m. ET TV ESPN3 Odds via DraftKings. Get up-to-the-minute college football odds here. When the 2021 season began, there weren’t many that would’ve called this matchup between Louisville and Wake Forest a pivotal game for …